Institute of Pharmaceutical Technology, Goethe University, Frankfurt am Main, Germany. Certara UK Limited, Simcyp Division, Level 2-Acero, 1 Concourse Way, Sheffield S1 2BJ, UK. University of Applied Sciences and Arts Northwestern Switzerland, Gründenstr. 40, 4132, Switzerland. Pion Inc. (UK) Ltd., Forest Row, East Sussex, UK. Institute of Pharmaceutical Technology, Goethe University, Frankfurt am Main, Germany. Electronic address: dressman@em.uni-frankfurt.de.